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Semaglutide is currently not on the WADA Prohibited List, though GLP-1 agonists as a class have been added to the WADA Monitoring Program since 2024 as a step toward potential future inclusion

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To date, equivocal responses to CM supplementation have been reported, which makes the performance-enhancing potential ambiguous

Loss of bladder or bowel control, numbness in the groin area, or rapidly progressing weakness in both legs suggest cauda equina syndrome