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The majority of natural GH secretion occurs during slow-wave (deep) sleep

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Meier TW, Thom NH, Evans PR, Leadlay PF

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In agreement with this, the ability of PA to protect cells against oxidative stress has been associated with inhibited ROS generation, increased GSH levels, and decreased lipid peroxidation (MDA), as shown in several studies ( An increased ROS level can directly or indirectly control the SIRT-1 enzyme (Salminen et al., 2013)