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In the current study, measurement of plasma dUrd concentration showed that pemetrexed administered at doses of 400700 mg m 2 produced consistent elevations in plasma dUrd, suggesting that plasma exposure to pemetrexed was sufficient to induce TS inhibition in patients

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doi: 10.1016/j.androl.2020.04.004 56 KitreyNDGruenwaldIAppelBShechterAMassarwaOVardiY