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While early treatment to correct for vitamin B12 deficiency is absolutely imperative to the babys recovery, it is unfortunately often a situation of too little, too late. Tragically, vitamin B12 deficiency in babies results in irreversible brain injury in approximately 50% of cases, even after B12 deficiency is corrected with supplementation

Targeting androgen signaling in ILC2s protects from IL-33-driven lung inflammation, independently of KLRG1

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Long-term effects, even in animals, have not been studied

The diagram below illustrates this proposed mechanism based on the cited literature [3] [4] [6]