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Autophagic flux tracing using tandem mRFP-GFP-LC3 probe showed that increase of autophagic flux caused by GSH depletion is augmented by rapamycin and attenuated by autophagic inhibitors 3-MA and Baf-A1 (Fig

The optical density, measured at 412 nm, is directly proportional to glutathione concentration in the sample

Fredriksson, L., Li, H

Temptation is very high, said spokesperson Vincent Maronilla

This stability may be attributed to mechanisms unrelated to hypoxia itself, such as the accumulation of tumor metabolites (e.g., succinate and fumarate), mitochondrial reactive oxygen species (ROS), or epigenetic alterations that suppress the activity of PHDs [11, 19,20,21,22]