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Cancers arising from tissue with a highly NAPRT are expression completely and irreversibly dependent on the NAPRT-regulated de novo pathway, while cancers deriving from tissues with the low level of NAPRT mainly rely on the NAMPT-mediated NAD + salvage pathway

The complex role of saprotrophic fungi in soil carbon cycling positions them as essential yet challenging agents in climate change mitigation, requiring careful management to balance their decomposition activity with their carbon sequestration potential across diverse ecosystems

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