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DNMT1 appears to be responsible for the maintenance of established patterns of DNA methylation, while DNMT3a and 3b seem to mediate establishment of new or de novo DNA methylation patterns

Molecular consequences of genetic variations in the glutathione peroxidase 1 selenoenzyme

The ZWF1 null mutant is a methionine auxotroph (Thomas et al., 1991), and shows decreased tolerance to oxidants, even in the presence of methionine, indicating that NADPH balance in the presence of methionine is critical (Campbell et al., 2016)