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The results showed that FA injection markedly enhanced the secretion of TNF- and IL-1 in the tubular epithelium, together with the increased infiltration of macrophage in the interstitial space, whereas LA supplementation downregulated the levels of these molecules

More importantly, we found a negative correlation between C16 and the PASI Score ( Figure 5B ), identifying C16 as a potential protective marker in psoriasis severity assessment

SCFAs, especially butyrate, play a central role in immune regulation

As the risk of ESRD imposed by RA is relatively higher in relatively young and healthy individuals, kidney-protective treatment, such as biologic agents, should be preferentially considered among these patients with RA

doi:10.1096/fba.2021-00022 13