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The chosen toxicants were given through drinking water while the chosen antioxidants (BCA, CoQ10, and PHL) were given intraperitoneally during the entire research

In such instances, the effective half-life (t 1/2eff )defined a priori based on accumulation ratiohas been proposed as a more relevant half-life parameter

Intestinal epithelium is constantly exposed to reactive oxygen metabolites from luminal contents or systemic oxidants which are rapidly removed by anti-oxidant systems, and a defect in this pathway leads to reversible or irreversible cellular injury 3