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confirmed increased small nerve fibre abundance in both skin and cornea Sarcoidosis-associated small fibre neuropathy Phase 2 RCT confirmed ARA-290 produced relief of neuropathy-related symptoms in sarcoidosis patients with moderate-to-severe neuropathic pain, with approximately 50% response rate versus placebo

*Correspondence: Farideh Shiraseb [email protected] Rastgoo [email protected] This article was submitted to Clinical Nutrition, a section of the journal Frontiers in Nutrition Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Scientific References Holmes B

Venugopal, B

Analytical-method validation concepts such as specificity, accuracy, precision, linearity, range, detection limit, quantitation limit, and robustness are described in ICH Q2(R2), while residual solvent and impurity expectations are addressed separately in ICH Q3C and ICH Q3A guidance