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The early clinical symptoms of CKD are not obvious, and the renal function gradually deteriorates in the later stage and eventually develops into uremia, that is, end-stage renal disease (ESRD)

FakhrolmobasheriMHosseiniMSShahrokhSGMohammadiZKahlaniMJMajidiSEet al

Vascular endothelial growth factor levels in diabetic peripheral neuropathy: a systematic review and meta-analysis

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After the war, antiseptics for wound cleaning took over, and the use of ozone began to draw renewed skepticism, with its benefits falling out of favor as its harmful effects became widely accepted