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Subsequently, we employed the incorporation of maleimide-liposomes, renowned for their capacity to disrupt the ROS delivery system, to ameliorate the drugs water solubility and pharmacokinetics, thereby enhancing its ROS-disruptive efficacy

(3) Administration and Metabolism: Mirabegron is administered orally once daily (2550 mg) and undergoes hepatic metabolism via multiple pathways, including dealkylation and oxidation

J Biol Chem (1996) 271:145049

Laboratory monitoring of electrolytes may be warranted in specific situations, such as persistent gastrointestinal symptoms, concurrent diuretic use, kidney disease, or older age