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Individualized lifestyle intervention in PCOS women (IPOS): a study protocol for a multicentric randomized controlled trial for evaluating the effectiveness of an individualized lifestyle intervention in PCOS women who wish to conceive

PMC 3123739

Given that the authors found that the top 10 key target proteins were markedly enriched in the cellular senescence pathways, they further used molecular docking to verify that the cellular senescence marker proteins p53, p21 and p16 are potential binding targets of AS-IV

D., et al., Homocysteine and alpha-lipoic acid regulate p44/42 MAP kinase phosphorylation in NIH/3T3 cells

In the trial, the results indicated that 1200 mg of ALA supplementation per day was well-tolerated without any adverse effect