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We order vitamin B12 and folate testing when a person with Down syndrome we are evaluating has symptoms described above, has a lab abnormality for which follow up testing of vitamin B12 and/or folate is indicated, or the person has a condition in which deficiency is common (e.g., celiac disease)

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doi:10.1016/j.bone.2005.04.017

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General Warning Please contact your veterinarian before using it and in case of unexpected effects