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Furthermore, propionic acid stimulates enteric neurons to release glutamate, which activates vagal afferents to transmit signals to the CNS, modulating mood-related brain circuits ( Foundation for SCFA production: dietary fiber (especially fructans and galactooligosaccharides) can significantly increase the abundance of Bifidobacterium and Lactobacillus in the gut (124), and these two bacterial groups are the main producers of SCFAs (100102)

however, these patterns differ from those observed between foreign-born groups and U.S.-born whites ( Microbial changes associated with dietary cultural adaptation: among foreign-born Koreans and Hispanics, individuals with high levels of dietary adaptation exhibit intestinal abundances that increasingly resemble those of U.S.-born whites

Amin et al

In the SIMGI model (an in vitro simulator of human digestion), a single dose of 0.166 g of PLAa widely used biodegradable plastic was followed by 72-h colonic fermentation

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