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Sdhof TC (2018) Towards an understanding of synapse formation

Sensory Stimuli: Overwhelming sensory input, such as loud noises, intense lights, and strong odors, can act as a catalyst for migraine episodes

Furthermore, activation of the mitogen-activated protein kinase (MAPK) pathway by -syn inhibits ubiquitination of DMT1, promoting DMT1 expression and enhancing iron influx into neurons (Bi et al