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This can lead to a shorter duration of B12 in the body, increasing the need for supplementation or injections to maintain adequate levels

During this process, electrons are pumped over the inner mitochondrial membrane, generating a proton gradient that in a subsequent step can trigger energy release to power the enzyme ATPase for the production of ATP from ADP

Since the constituents of dietary extracts are not completely absorbed from the gastrointestinal tract, the absolute bioavailability specifies the percentage of compounds that are taken up after oral ingestion

While numerous studies have demonstrated encouraging preclinical outcomes using polyphenols such as curcumin, quercetin, resveratrol, and betulin encapsulated in lipid- or polymer-based nanocarriers, their translational promise remains highly variable

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