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The underlying mechanism of this impaired engulfment is linked to the disruption of the Rho GTPase signaling, which is crucial for phagocytosis by pyocyanin-generated ROS (108, 136)

To base this scenario on admittedly indirect empirical evidence, I first highlight similarities between SARS-CoV-2 and HIV-1 that are related to HIV-1s effects on DNA damage, dsDNA-sensing, inflammation, and autoimmunity

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