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Nanomedicine And Nanotheranostics: Special Focus on Imaging of Anticancer Drugs Induced Cardiac Toxicity

doi: 10.1590/fst.24219 79

Subsequent efforts to identify the enzyme responsible for cGAMP production led to the characterization of cyclic GMP-AMP synthase (cGAS), a cytosolic DNA sensor that directly binds double-stranded DNA and catalyzes cGAMP synthesis upon activation (Sun et al., 2013)