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When NAD levels decline, it results in a decrease in cellular energy, which can also be described as mitochondrial dysfunction a condition that is implicated in most chronic illnesses, including diabetes, autoimmune disorders, Alzheimers, multiple sclerosis and many more

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These changes may cause disordered sympathetic and parasympathetic activity (158, 360) as well as PEM and cognitive dysfunction (363)

indeed, plant foods are the major dietary sources of Se and its amount in diet depends by several factors, such as soil Se concentrations, soil pH, geographic location, types and amounts of food consumed, etc