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For example, extension of rat half-life from 0.5 to 0.75 h (with no change in CL u ) lowers the dose by about 4-fold

Biemann K

doi: 10.3390/jcm10173880 60 ShapiroJCohenNAShalevVUzanAKorenOMaharshakN

Glutathione is widely studied in cell and laboratory work, but oral glutathione has poor bioavailability, and the value of injectable glutathione for raising tissue levels or producing clinical benefits is not well established [11] [12]