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Description

T.VantlerM.et al (2006)

Chestnut Ridge, NY: Par Pharmaceutical

That discovery launched decades of research into one of the most unusual peptides in neuroscience

Although 6-phosphoglucono--lactone is hydrolytically unstable and can undergo spontaneous (nonenzymatic) ring-opening at a significant rate, this hydrolysis reaction is greatly accelerated in the cell by the enzyme 6-phosphogluconolactonase (EC 3.1.1.31)