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Despite this, the ability of NZs to eradicate bacterial infections is severely hampered by their inadequate catalytic activity

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23,24,25 Therefore, a series of new molecular targeted therapeutic drugs to block COPD progression is under development

Both epidemiologic and experimental studies have evidenced that pesticides exposure affects central nervous systems, probably via epigenetic modifications (Yu et al., 2021), such as up-regulation of miRNA-181 that drives the neuronal cells apoptosis as observed by Zhao et al