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It is well established that host metabolism, including host diet, environmental factors, and immune status, drives the ecological environment of the GI tract [33,34,35]

Their discovery revealed that microbes in the oral cavity may play an unappreciated role in initiating the digestion of gluten during its first exposure to the gastrointestinal tract

Proc Natl Acad Sci USA 108 , 1140511410 (2011)

PMID: 57 BoaruDLFraile-MartinezODe Leon-OlivaDGarcia-MonteroCDe Castro-MartinezPMiranda-GonzalezAet al

Estrogen and progesterone work together to boost serotonin (your calming neurotransmitter) during this phase, which is why many women feel calmer and have better sleep during this phase, if everything is in balance.(20-22) Even though both hormones increase during this time, progesterone becomes the more dominant hormone