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Children under the age of 16 cannot be prescribed this medication

or the decision to submit the paper for publication

The jump from 0.5 mg to 1.0 mg is the largest proportional increase in the entire titration schedule, doubling your dose again

Severe hypokalaemia (low blood potassium) is rare but can develop in some cases, particularly in severe megaloblastic anaemia or in patients taking certain medications such as diuretics

People with unexplained low platelets plus any of the following: iron deficiency, anemia, neuropathy, bone pain, chronic diarrhea or constipation, bloating, dermatitis herpetiformis, autoimmune thyroid disease, type 1 diabetes, or family history of celiac disease