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Ninfali P, Antonini E, Frati A, et al

Detoxification happens in two phases: Phase I : Toxins undergo chemical modifications Phase II : Glutathione binds to these modified toxins, creating water-soluble compounds for easy elimination During these phases, harmful substances are transformed into mercapturic acid through specific enzymatic reactions

For analysis, replicate blots were each derived from the same experiment and processed in parallel

Interestingly light-induced photo-oxidative stress resulted in activation of the NF-B signaling pathway, which has been shown to be in response to oxidative stress (Wu et al., 2005)

2 The number of patients in Japan is estimated to be approximately 10,000