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Alternatively, as the fractional enrichment of GlxH2 (Glx FE ) can be assessed with the help of its 13 C-satellites, it can be used as a normalizing factor to report labelling of glutamate or GABA

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Pyruvate, a metabolic product of glycolysis, can be converted to lactate and secreted out of a cell, or it can enter the mitochondria for consumption in the TCA

[1] During injury processes such as ischemia and traumatic brain injury, the action of glutamate transporters may fail, leading to toxic buildup of glutamate