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CA: A Cancer Journal for Clinicians

Lower pools of reduced glutathione have been associated with the severity of the autoimmune response, cell apoptosis (death), and autoantibody production

Human glutathione S-transferases- and NAD(P)H:quinone oxidoreductase 1-catalyzed inactivation of reactive quinoneimines of amodiaquine and N-desethylamodiaquine: possible implications for susceptibility to amodiaquine-induced liver toxicity