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The redox state significantly influences the gut microbiota's composition and activity, affecting microbial metabolism and their interactions with the host

TBI induces arachidonic acid release from cell membranes and increases 20-hydroxyeicosatetraenoic acid (20-HETE), a metabolite of the arachidonic acid pathway (Figure 2)

Hazel JR, Williams EE, Livermore R, Mozingo N

Indeed, the process of adaptation to glutamine deprivation weakens the response to hypoxia, which normally strongly induces the expression of glycolytic enzymes 83

CDAHFD-induced liver injury, steatosis, and oxidative stress as shown by the increased serum alanine aminotransferase and aspartate aminotransferase activities, and hepatic triglyceride and lipid peroxide levels, respectively, but -alanine alleviated these changes