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Most autoantibodies are of the immunoglobulin G (IgG) isotype, which has a long plasma half-life and potent effector functions

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7-9 Investigation of this relationship is important since deficiency of B 12 may not only exacerbate myelopathic symptoms in DCM but may also hinder neurological recovery, since B 12 is essential for myelination

Qiao Zhou, [email protected] These authors have contributed equally to this work This article was submitted to Cell Physiology, a section of the journal Frontiers in Physiology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Metwally declare that they have no competing interests