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NAC did, however, lead to a significant reduction in cardiac toxicity

A national assessment of T2 staging for intrahepatic cholangiocarcinoma and the poor prognosis associated with multifocality

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Similarly, Cys undergoes rapid oxidation to its disulfide moiety upon delivery, thereby generating an inactive disulfide cystine (Cys-Cys), and due to its poor solubility, the sulfhydryl functional group on Cys is rendered temporarily inaccessible [28]