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However, novel inflammatory mediators have gone beyond these classical molecules and become emerging core participants in the pathogenesis of IBD and CRC

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[3] Another possible effect is a rosacea-like dermatitis: some patients develop erythema (redness), fine pimples or pustules, and burning in a pattern that resembles rosacea when using topical steroids on the face, a phenomenon sometimes called steroid rosacea. Additionally, steroids can precipitate or worsen acneiform eruptions, essentially steroid-induced acne, characterized by small, uniform papules and pustules

Specifically, it seemed that BPC-157 could regulate the phosphorylation level of extracellular signal-regulated kinases 1 and 2 (ERK1/2)