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J.DugoC.BarkerA.et al (2023)

In addition to CSCs and DTPs, oncogenic mutationsparticularly KRAS mutationsalso play a pivotal role in driving mitochondrial metabolic remodeling and promoting chemoresistance [67,68,69]

and upregulate antioxidant machinery, thereby supporting normal cellular signaling at lower doses [263, 275]

Telo ima odreenu koliinu karnitina i uglavnom je dovoljna za normalno funkcionisanje ali problem nije njegov totalni nedostatak, nego nedovoljno L karnitina u trenutku kada telo pokuava da sagoreva mast intenzivnije, ba tokom treninga ili dijete