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Samples were thawed on ice, diluted 5-fold with diluent, and 50 L aliquots were assayed in duplicate using the solid phase Mouse Thrombopoietin Quantikine ELISA Kit (Biotechne, Minneapolis, MN catalog #MTP00), quantified to a standard control curve displaying an R 2 = 0.999

Recent studies have investigated the relationship between statin use and glaucoma, producing varying outcomes

In renal biopsy tissue studies of CKD patients and mice models including UUO and renal ischemia-reperfusion injury, downregulation of GPx4 and upregulation of 4-hydroxynonenal were observed

Unlike the traditional one drug-one target-one disease paradigm, network-based drug discovery reveals disease mechanisms from a holistic perspective, fully considering the complexity of biological systems [10]

Arrows represent direction of change in APOE4 vs