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Restless legs syndrome (RLS), also called Willis-Ekbom disease (WED) or Ekbom syndrome, is most frequently characterized by the uncontrollable urge to shake or move your legs

In diet-induced obese (DIO) mouse models, 5-Amino-1MQ treatment produced significant reductions in body weight, white adipose tissue mass, and adipocyte cell size without significant effects on food intake suggesting a metabolic rather than appetite-suppressing mechanism