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lung diseases such as asthma, acute respiratory distress syndrome and chronic obstructive pulmonary disease

doi: 10.1038/s41598-025-12644-w 178 WangYWeiXWuM

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Importantly, in the patients bearing tumors with NRF2-KEAP1 alteration a significantly increase in expression of NRF2 target genes was observed, such as NQO1, and the enzymes responsible for GSH synthesis, GCLC and GCLM, which indicates that GSH levels are also higher (Fig