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The trial, which is testing people at 150 sites in the US, Germany, Turkey, South Africa, Brazil and Argentina, will collect data on the safety and efficacy of the vaccine for another two years

Since it can be formed from these three amino acids in the body, it is deemed non-essential, in that it does not have to be obtained from food

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Furthermore, a more recent study has shown decreased TPP levels in plasma from ASD children compared to healthy controls (147), suggesting either lower consumption or an impaired absorption from the gastrointestinal tract, providing a link between thiamine metabolism and the gut microbiome, which has been considered in the context of ASD (148)