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These programmes provide support from healthcare professionals including dietitians, who can help ensure that calorie restriction is achieved safely and without compromising gut health or overall nutritional status

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OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28

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Importantly, even moderate VGAT alterations, as detected in SMA mice with a modest but significant increase at both the early symptomatic and late disease stages, can significantly affect inhibitory synaptic currents and physiological responses [75]

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Importantly, a study showed intestinal microbiota metabolism of dietary L-Cn to produce trimethylamine-N-oxide (TMAO), which accelerated the development of atherosclerosis (35)

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