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To clear histamine from the body, particularly in the central nervous system, the body relies on an enzyme called Histamine N-Methyltransferase (HNMT)

When vitamin B12 was 358.7 pg/mL, each 10 pg/mL increase was associated with a 4% rise in clinical pregnancy rate (adjusted OR = 1.04, 95% CI: 1.001.08, P = 0.03)