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The percentage of patients who withdrew from the study due to adverse events was 5.3% and 4.7% for the Reclast and placebo groups, respectively

90 Moreover, tryptophan metabolism mediated by IDO affects not only the Kyn pathway but also other pathways, such as the purine, nicotinamide, and pyrimidine metabolism pathways, ultimately leading to decreased T-cell function

29 372-379 2009 Homo sapiens brenda Critton, D.A

Reduced Inflammation and Pain It modulates pro-inflammatory cytokines like IL-6 and TNF-, reducing pain and swelling without the gastrointestinal risks of NSAIDs

The platform and the entire digital ecosystem proposed by the project acquire a dual significance in the research objectives