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Hartman (171) conducted an IF intervention in 6 children aged 27 years with epilepsy who were poorly controlled by the ketogenic diet, and the study found that despite hunger-related adverse effects, 3 children persisted with the IF combined ketogenic diet treatment for 2 months, and 4 children experienced transient improvements in seizure control

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The use of cyclosporine A as monotherapy was reported in 137 patients and provided an ORR of 83.2% (95% CI, 72.3-94.1, I 2 , 58%), whereas 124 patients were reported to receive cyclosporine combined with corticosteroids, providing an ORR of 77.3% (95% CI, 69.9-84.7, I 2 , 0%)