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Curcumin increases ADAMTS18 gene expression and restores ccRCC sensitivity to sunitinib, and this regulation can be reversed by ferroptosis inhibitors, indicating that curcumin mediates ferroptosis in ccRCC through ADAMTS18 (178)

"Moonstone contains clinically significant amounts of citrate-as-alkali to increase urine citrate and pH, and may make the kidneys less hospitable to the formation of kidney stones, namely: calcium oxalate, cystine and uric acid stones

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Weight-based dosing calculations sometimes appear in discussions, with suggestions of approximately 2.5 to 5 mcg per pound of body weight daily