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Representative flow cytometry results show BMDM cell polarization under different treatment conditions in vitro

408 Within this complex interplay of diet, metabolism, and inflammation, IL-17 has been identified as a key player in metabolic dysregulation associated with HFD, where inhibiting IL-17A production or blocking its receptor can attenuate obesity by enhancing adipose tissue browning and energy dissipation

When cellular cholesterol levels are below the threshold, SREBPs are activated and translocated to the nucleus to accelerate the transcription of HMGCR and other genes involved in cholesterol synthesis [37, 38]

In a 2020 study, researchers reported that certain antimicrobial defense peptides (AMPs) could not only fight off microbes, but boost the immune system when needed, or reduce inflammation in cases where the immune system was overreacting

doi: 10.1016/j.fsi.2010.02.017 226 NedaeiS.NooriA.ValipourA.KhanipourA