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These findings indicate an important role for inflammation and chronic stress in the pathophysiology of depression and point to the HPA axis as an important therapeutic target

Garlic oil upregulated the activity of various antioxidant enzymes and expression of pro-apoptotic effectors like Bax and Caspase-3 and downregulated the expression of the anti-apoptotic genes -arrestin-2, Bcl-2, and Bcl-X (76)

Therefore, the induction of ferroptosis in tumor cells has emerged as a promising approach to overcome apoptosis resistance and increase sensitivity to radiotherapy

42 , 43 In AML, data about ferroptosis are scarce