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Proteomics in the kidney marrow between young-adult and aged killifish showed age-dependent enhanced oxidative stress buffering, including increased glutathione metabolism and upregulation of peptides involved in detoxification processes, which may help clear accumulated metabolic byproducts, such as alcohols, hydroxy compounds and aldehydes

The samples were then embedded in resin blocks and polymerized at 60 C for 24 h

Targeted deletion of hepatic Igf1 in TRAMP mice leads to dramatic alterations in the circulating insulin-like growth factor axis but does not reduce tumor progression

62,249 particles) and State 2 (2%, 21,642 particles)

known as slow wave sleep) showed no significant changes (F (8,109.970) = 1.342, p = 0.230)