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Key Takeaways BPC 157 is a stable gastric pentadecapeptide with significant cytoprotective properties, promoting healing and integrity of the gastrointestinal tract and other tissues

Figure 5 Downstream cellular mediators of Dihexa protection Activation of the receptor tyrosine kinase c-Met leads to the recruitment of many signaling mediators and ultimately the activation of downstream signals, most notably Akt-TOR and Ras-ERK (Organ and Tsao, 6A)

Scientific Overview Dihexa binds to hepatocyte growth factor (HGF) with high affinity and potentiates its activity at the c-Met receptor in research settings

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The over-the-counter (OTC) Monograph Drug User Fee Program (OMUFA) arrears and paid facilities lists have been updated by FDA on its website