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3 Biotech 10(12):522 Meng J et al (2021) Precision redox: the key for antioxidant pharmacology

Beyond direct BBB injury, studies using asthma models have shown that increased acetylcholinesterase activity and decreased Na+, K+-ATPase activity contribute to a proinflammatory microenvironment, indirectly affecting BBB function and leading to anxiety-like behaviors in mice [385, 386]