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Currently, GABAergic drugs are used in the second or third line of treatment of AUD and mitigation of alcohol withdrawal

By promoting SCFA-producing bacteria and modulating bile acid pathways, probiotics increase the efficacy of standard treatments

For inflammatory stimulation, KCs cells were treated with E2 for 6 h followed by stimulation with LPS for 4 h for RNA isolation and RT-qPCR

doi: 10.1186/s12918-017-0464-7 99 ChekerovRHilpertFMahnerSEl-BalatAHarterPDe GregorioNet al

Of note, NO avidly binds iron and is known to attack the active sites of a multitude of proteins, including heme and iron-sulfur clusters ([Fe-S]) [1]