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G6PD inhibition has been shown to impair cellular migration through ROS-dependent inhibition of protein phosphatases involved in cytoskeletal rearrangement, suggesting that chronic ROS accumulation in G6PD-d may inhibit B1 migration necessary for IgM OSE production 87,144,145 (Fig

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Nafarelin and buserelin (GnRH analogs): Approved or used clinically in some countries intranasally for endometriosis or prostate cancer

Genome editing human pluripotent stem cells to model beta-cell disease and unmask novel genetic modifiers