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This review will focus on how mitochondria in the lung regulate these processes and their involvement in acute and chronic lung diseases

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Adv Healthcare Mater, 2022, 11: 2101926 Acknowledgements This work was supported by the National Natural Science Foundation of China (62175262), the Science and Technology Innovation Program of Hunan Province (2022RC1201), the Fundamental Research Fund for the Central South Universities (2020CX021), the Key R & D plan of Hunan Province (2022SK2101), and the Scientific Research Launch Project for new employees of the Second Xiangya Hospital of Central South University

However, it remains unknown whether Nrfs can bind to the Tim23 promoter to regulate its transcription and the subsequent activation of Drp1, thereby influencing ferroptosis during MASH progression